Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078613 | 0.86 | HPGD (0.50) | SMN1; SMN2MAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5634500 | 0.83 | L3MBTL1 (0.52) | SMN1; SMN2MAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL13292672 | 0.82 | PRNP (0.36) | SMN1; SMN2MAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL17999737 | 0.82 | ALDH1A1 (0.35) | SMN1; SMN2MAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL8357735 | 0.80 | NPC1 (0.55) | SMN1; SMN2MAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL14423074 | 0.79 | ALDH1A1 (0.50) | F2RSMN1; SMN2HPGDALDH1A1L3MBTL1 | |
| SCHEMBL442079 | 0.79 | ATM (0.51) | SMN1; SMN2MAPTALDH1A1ATMCYP2C19 | |
| SCHEMBL13851050 | 0.75 | ATM (0.37) | MAPTALDH1A1L3MBTL1ATMPRNP | |
| SCHEMBL3117691 | 0.75 | ALDH1A1 (0.33) | SMN1; SMN2MAPTHPGDALDH1A1TP53 | |
| SCHEMBL3113328 | 0.75 | LMNA (0.32) | MAPTHPGDALDH1A1L3MBTL1PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869427-A | Substituted thiophene derivative and plant disease control agent comprising the same as active ingredient | MITSUI CHEMICALS, INC. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0841336-A1 | Substituted thiopene derivative and plant disease control agent comprising the same as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-05-13 | — | — | EP | disclosed |