Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356144 | 0.86 | MAPT (0.45) | ESR1THRATHRBMAPTLMNA | |
| SCHEMBL8358085 | 0.75 | MAPT (0.51) | ESR1THRATHRBMAPTPLA2G4B | |
| SCHEMBL9322138 | 0.74 | THRA (0.54) | ESR1THRATHRBMAPTPLA2G4B | |
| SCHEMBL8746014 | 0.74 | ESR1 (0.55) | ESR1THRATHRBMAPTPLA2G4B | |
| SCHEMBL16742372 | 0.73 | MAPT (0.63) | ESR1MAPTPLA2G4BLMNAALDH1A1 | |
| SCHEMBL11511728 | 0.73 | ALDH1A1 (0.46) | ESR1THRATHRBMAPTPLA2G4B | |
| SCHEMBL16516336 | 0.73 | MAPT (0.63) | ESR1MAPTPLA2G4BLMNAALDH1A1 | |
| SCHEMBL6933094 | 0.72 | ESR1 (0.52) | ESR1THRATHRBMAPTPLA2G4B | |
| SCHEMBL2249192 | 0.72 | ESR1 (0.52) | ESR1THRATHRBMAPTPLA2G4B | |
| SCHEMBL30692371 | 0.72 | ESR1 (0.44) | ESR1THRATHRBMAPTPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910578-A | NOVEL AZO DYES USEFUL FOR DYEING OR PRINTING SYNTHETIC MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-08 | — | — | US | disclosed |