Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353844 | 0.91 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1PKMLMNATRPM8 | |
| SCHEMBL2658210 | 0.88 | PKM (0.51) | ALDH1A1PKMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL6959399 | 0.80 | HTT (0.46) | ALDH1A1PKMSMN1; SMN2RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL27680689 | 0.78 | HTT (0.45) | ALDH1A1PKMSMN1; SMN2RAB9AMAPT | |
| Bromide SCHEMBL5529731 | 0.78 | HTT (0.45) | ALDH1A1PKMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL9789365 | 0.76 | FDPS (0.42) | ALDH1A1PKMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL6959394 | 0.76 | FDPS (0.42) | ALDH1A1PKMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL930138 | 0.75 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1PKMSMN1; SMN2RAB9A | |
| SCHEMBL15897511 | 0.75 | ALDH1A1 (0.42) | ALDH1A1PKMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL27521697 | 0.75 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1PKMSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |