Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.64 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | VDR | P11473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963211 | 0.88 | CCR2 (0.73) | CCR2LMNAVDRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13900126 | 0.79 | F10 (0.55) | CCR2F10LMNAALDH1A1MAPT | |
| SCHEMBL1573798 | 0.79 | PLA2G10 (0.78) | CCR2PLA2G10F10 | |
| SCHEMBL29258469 | 0.78 | LMNA (0.46) | CCR2F10LMNAVDRSMN1; SMN2 | |
| SCHEMBL3962697 | 0.77 | CCR2 (0.62) | CCR2F10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3966109 | 0.76 | CCR2 (0.78) | CCR2ALDH1A1CYP1A2 | |
| SCHEMBL30589608 | 0.76 | PTGS2 (0.68) | CCR2LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL13900120 | 0.75 | F10 (0.54) | CCR2F10LMNACYP1A2PPARG | |
| SCHEMBL13900123 | 0.75 | PTGS2 (0.59) | CCR2F10 | |
| SCHEMBL27636281 | 0.74 | CCR2 (0.54) | CCR2PLA2G10F10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003044014-A1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-05-30 | — | — | WO | disclosed |