Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157509 | 0.80 | ALDH1A1 (0.47) | AOC3ALOX5CHRNB2CHRNA4SLC1A3 | |
| SCHEMBL27587442 | 0.80 | CPA3 (0.47) | CHRNB2CHRNA4SLC6A3SLC1A3SLC1A2 | |
| SCHEMBL4130181 | 0.80 | CPA3 (0.47) | CHRNB2CHRNA4SLC6A3SLC1A3SLC1A2 | |
| SCHEMBL21094406 | 0.77 | AOC3 (0.47) | AOC3CHRNB2CHRNA4SLC6A2SLC6A4 | |
| SCHEMBL14985679 | 0.76 | LTA4H (0.47) | SLC1A3SLC1A1 | |
| SCHEMBL2311799 | 0.75 | MMP9 (0.42) | ALOX5APPNPC1RAB9ASLC1A3 | |
| SCHEMBL13496240 | 0.75 | SLC6A2 (0.41) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25434926 | 0.75 | SLC1A3 (0.46) | AOC3ALOX5CHRNB2CHRNA4SLC1A3 | |
| SCHEMBL18936422 | 0.75 | NPC1 (0.44) | ALOX5APPNPC1RAB9AKMT2A | |
| SCHEMBL9980206 | 0.74 | LTA4H (0.38) | ALOX5APPNPC1RAB9ASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |