Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359447 | 0.84 | PDE3B (0.41) | HSP90AA1PDE3BPDE3ATSHRALDH1A1 | |
| SCHEMBL8359371 | 0.81 | ALDH1A1 (0.46) | SRD5A1SRD5A2TSHRALDH1A1TP53 | |
| SCHEMBL28958552 | 0.77 | KDM4E (0.48) | ALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL8359369 | 0.77 | NAMPT (0.35) | TSHRSMN1; SMN2CA1CA2TDP1 | |
| SCHEMBL515808 | 0.74 | TRPA1 (0.44) | SRD5A2TSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3855331 | 0.72 | PDE3B (0.43) | SRD5A1SRD5A2HSP90AA1DHODHPDE3B | |
| SCHEMBL29293278 | 0.71 | PDE3B (0.41) | PDE3BPDE3AALDH1A1ACHEAHR | |
| SCHEMBL19181316 | 0.69 | EGLN1 (0.42) | SRD5A1SRD5A2POLB | |
| SCHEMBL31106531 | 0.69 | RXFP1 (0.56) | DHODHTSHRALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL29292325 | 0.67 | PDE3B (0.38) | PDE3BPDE3AACHEAHRMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003039540-A2 | D-AMINO ACID OXIDASE INHIBITORS FOR LEARNING AND MEMORY | SEPRACOR INC. (US) | 2003-05-15 | — | — | WO | disclosed |