SCHEMBL8359479

SCHEMBL8359479

COc1ccc(-c2ccnnn2)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.43
EP300 Q09472 1/20 0.42
KAT8 Q9H7Z6 1/20 0.42
MAPT P10636 5/20 0.40
LMNA P02545 2/20 0.40
IMPDH2 P12268 1/20 0.40
IMPDH1 P20839 1/20 0.40
NQO1 P15559 1/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
RAB9A P51151 1/20 0.37
PLK1 P53350 1/20 0.36
USP2 O75604 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30702995 0.81 RAB9A (0.48) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL148972 0.81 RAB9A (0.48) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL12019841 0.74 IDO1 (0.64) IDO1EP300KAT8MAPTLMNA
SCHEMBL7753164 0.74 IDO1 (0.64) IDO1EP300KAT8MAPTLMNA
SCHEMBL12019777 0.74 IDO1 (0.64) IDO1EP300KAT8MAPTLMNA
Phenol SCHEMBL2225931 0.74 VCP (0.43) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL3086671 0.73 HTR2C (0.44) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL16731967 0.72 ALDH1A1 (0.32) LMNAALDH1A1SMN1; SMN2RAB9AALOX15
SCHEMBL419307 0.72 IDO1 (0.73) IDO1EP300KAT8MAPTLMNA
SCHEMBL4190081 0.72 IDO1 (0.41) IDO1EP300KAT8MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0896250-A2 Hardenable photoimageable compositions MORTON INTERNATIONAL, INC. (US) 1999-02-10 EP claimed
EP-0896250-A2 Hardenable photoimageable compositions MORTON INTERNATIONAL, INC. (US) 1999-02-10 EP disclosed
US-5858615-A CONTAINING TRIAZINE COMPOUND MORTON INTERNATIONAL, INC. (US) 1999-01-12 US disclosed