Phenol

Phenol

SCHEMBL8359665

Cc1c(O)ccc(N)c1N.Oc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
GLA P06280 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
ALDH1A1 P00352 8/20 0.42
ALOX15 P16050 5/20 0.42
GAA P10253 5/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
HSD17B10 Q99714 3/20 0.42
HTT P42858 3/20 0.42
HPGD P15428 3/20 0.42
MAPT P10636 3/20 0.42
ALOX12 P18054 3/20 0.42
KDM4E B2RXH2 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603633 0.87 ALOX15 (0.46) ALDH1A1ALOX15GAAMEN1KMT2A
Phenol SCHEMBL28131026 0.78 CYP3A4 (0.52) TDP1CA12CA1CA2GLA
Phenol SCHEMBL7526424 0.73 TDP1 (0.46) TDP1CA12CA1CA2GLA
Phenol SCHEMBL26123048 0.73 CA2 (0.58) TDP1CA12CA1CA2GLA
SCHEMBL4815999 0.73 ALDH1A1 (0.44) TDP1ALDH1A1ALOX15GAAMEN1
Phenol SCHEMBL6118083 0.72 ALOX15 (0.54) TDP1CA12CA1CA2GLA
Phenol SCHEMBL27518136 0.72 ALOX15 (0.57) TDP1CA12CA1CA2GLA
SCHEMBL27739272 0.72 KMT2A (0.47) TDP1CA12CA9ALDH1A1ALOX15
SCHEMBL525507 0.71 ALDH1A1 (0.48) TDP1ALDH1A1ALOX15GAAMEN1
Phenol SCHEMBL10410814 0.70 CA14 (0.69) TDP1CA12CA1CA2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5910548-A EXCELLENT MOISTURE RESISTANCE AND ELELCTRICAL CHARACTERISTICS SHELL OIL COMPANY (US) 1999-06-08 US disclosed
US-5886134-A FROM ARYLENE DICYANATES AND ARYLENEDIOXYDIPHENYLENEBISMALEIMIDES NATIONAL SCIENCE COUNCIL OF REPUBLIC OF CHINA (TW) 1999-03-23 US disclosed
US-4251411-A BY REACTING A POLYHYDROXY COMPOUND, AN AQUEOUS POLYMER DISPERSION AND SOME OF THE RECYCLE POLYMER BASF AKTIENGESELLSCHAFT (DE) 1981-02-17 US disclosed