Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767061 | 0.86 | PLK1 (0.59) | MTNR1AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL17414607 | 0.82 | P2RX1 (0.57) | MTNR1AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL29502160 | 0.81 | KDM4E (0.62) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL146258 | 0.81 | KDM4E (0.62) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL1558756 | 0.81 | BRAF (0.65) | MTNR1AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL7502111 | 0.81 | HPGD (0.61) | MTNR1AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL18661182 | 0.81 | MTNR1A (0.55) | MTNR1AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL7984549 | 0.81 | TYK2 (0.62) | MTNR1AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL20439234 | 0.80 | NR1H4 (0.56) | HPGDHTTCYP2C9CYP1A2RAF1 | |
| SCHEMBL1986986 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026652-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
| US-4107311-A | ANTI-FERTILITY AGENTS, ABORTIFACIENTS | SANDOZ, INC. (US) | 1978-08-15 | — | — | US | disclosed |