Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361046 | 0.99 | PTGS2 (0.62) | PTGS2AKR1C3AKR1C2PTGS1MAPT | |
| SCHEMBL8354816 | 0.95 | LMNA (0.59) | PTGS2AKR1C3AKR1C2NPSR1 | |
| SCHEMBL8353887 | 0.95 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL8354810 | 0.94 | LMNA (0.58) | PTGS2AKR1C3AKR1C2NPSR1 | |
| SCHEMBL8358997 | 0.94 | PTGS2 (0.56) | PTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL8360473 | 0.94 | PTGS2 (0.55) | PTGS2AKR1C3AKR1C2 | |
| SCHEMBL8356524 | 0.93 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL8359033 | 0.87 | LMNA (0.49) | PTGS2PTGS1NPSR1 | |
| SCHEMBL8360277 | 0.87 | LMNA (0.59) | PTGS2AKR1C3AKR1C2NPSR1 | |
| SCHEMBL8360565 | 0.87 | PTGS2 (0.59) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |