Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.56 |
| ▸ | MMP8 | P22894 | 9/20 | 0.56 |
| ▸ | MMP9 | P14780 | 7/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 8/20 | 0.54 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | MMP14 | P50281 | 3/20 | 0.51 |
| ▸ | CCKBR | P32239 | 2/20 | 0.51 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CASP4 | P49662 | 1/20 | 0.51 |
| ▸ | CASP5 | P51878 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242045 | 0.95 | EDNRA (0.55) | MMP2MMP8MMP9EDNRAMMP1 | |
| SCHEMBL8363817 | 0.92 | MMP2 (0.62) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL14177783 | 0.89 | CCKBR (0.61) | MMP2MMP8MMP9MMP1CCKBR | |
| SCHEMBL8245264 | 0.88 | MMP2 (0.58) | MMP2MMP8MMP9MMP1CCKBR | |
| SCHEMBL8242675 | 0.88 | MMP2 (0.58) | MMP2MMP8MMP9MMP1CCKBR | |
| SCHEMBL8363816 | 0.87 | MMP8 (0.58) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL14177510 | 0.87 | CCKBR (0.61) | MMP2MMP8MMP9MMP1CCKBR | |
| SCHEMBL8360545 | 0.86 | MMP2 (0.55) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL8426483 | 0.86 | MMP2 (0.62) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL8426512 | 0.85 | MMP2 (0.63) | MMP2MMP8MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932853-A1 | Novel depsipeptides and process for preparing same | Cubist Pharmaceutical Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2003014147-A1 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | CUBIST PHARMACEUTICALS, INC. (US) | 2003-02-20 | — | — | WO | disclosed |