SCHEMBL8360759

SCHEMBL8360759

Cc1ccc(N(c2ccc(C)cc2)c2cc(CCl)ccc2CCl)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
IDO1 P14902 1/20 0.31
CNR2 P34972 7/20 0.31
CNR1 P21554 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5617928 0.78 ALDH1A1 (0.42) CYP2C19ALDH1A1TSHRIDO1CNR2
SCHEMBL14948436 0.73 SLC6A2 (0.39) KMT2ANPSR1CYP2C19ALDH1A1TSHR
Hydrochloric Acid SCHEMBL8923137 0.73 CXCR4 (0.35) KMT2AALDH1A1TSHR
SCHEMBL14948375 0.72 ALDH1A1 (0.41) KMT2ACYP2C19ALDH1A1TSHRCNR2
SCHEMBL4349827 0.70 BACE1 (0.42) KMT2ANPSR1IDO1
Methylene Chloride SCHEMBL10948817 0.69 ALDH1A1 (0.50) NPSR1CYP2C19ALDH1A1TSHRIDO1
SCHEMBL45443 0.69
SCHEMBL27848176 0.68 NPSR1 (0.39) KMT2ANPSR1ALDH1A1
SCHEMBL6914100 0.68 ESR1 (0.37) KMT2ANPSR1CYP2C19TSHR
Trimethylammonium SCHEMBL9757620 0.67 IDO1 (0.46) ALDH1A1TSHRIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817430-A POLYARYLENEVINYLENE POLYMER XEROX CORPORATION (US) 1998-10-06 US claimed
US-5876865-A POLYARYLENEVINYLENE RESIN XEROX CORPORATION (US) 1999-03-02 US disclosed
US-5817430-A POLYARYLENEVINYLENE POLYMER XEROX CORPORATION (US) 1998-10-06 US disclosed