Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966221 | 0.95 | TDP1 (0.38) | TDP1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8911745 | 0.69 | MAPT (0.36) | TDP1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL1388443 | 0.68 | DHODH (0.38) | TDP1MAPTL3MBTL1KMT2ASLC6A2 | |
| SCHEMBL9434825 | 0.68 | DHODH (0.38) | TDP1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9212581 | 0.67 | DHODH (0.38) | TDP1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL1388453 | 0.67 | TDP1 (0.35) | TDP1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL4933057 | 0.61 | TDP1 (0.62) | TDP1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL17965761 | 0.61 | TDP1 (0.61) | TDP1MAPTL3MBTL1ALDH1A1KMT2A | |
| E1501 SCHEMBL29824487 | 0.61 | ALDH1A1 (0.63) | TDP1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL19588519 | 0.61 | ALDH1A1 (0.70) | TDP1MAPTL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999045926-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS ANTI-INFLAMMATORY AND IMMUNOMODULATORY AGENTS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1999-09-16 | — | — | WO | disclosed |