SCHEMBL8363571

SCHEMBL8363571

Cc1cccc(N(c2ccc(-c3ccc(N(c4cccc(C)c4)c4cccc5ccccc45)cc3)cc2)c2cccc3ccccc23)c1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.43
CYP1A2 P05177 2/20 0.39
CYP2A6 P11509 2/20 0.39
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
MAPT P10636 2/20 0.35
NR1I2 O75469 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTR2B P41595 1/20 0.35
CYP51A1 Q16850 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DHFR P00374 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16344091 1.00 SIGMAR1 (0.43) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL18069063 1.00 SIGMAR1 (0.43) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL13809112 0.98 SIGMAR1 (0.42) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL14018316 0.97 SIGMAR1 (0.41) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL10053548 0.97 SIGMAR1 (0.41) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL4579204 0.97 SIGMAR1 (0.41) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL1813433 0.97 SIGMAR1 (0.41) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL18780369 0.97 SIGMAR1 (0.41) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL14672919 0.95 SIGMAR1 (0.42) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL12757486 0.94 HSD17B1 (0.43) SIGMAR1CYP1A2CYP2A6HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739701-B2 A NOVEL COMPOSITION FOR RADIATION IMAGING DETECTOR AND A RADIATION IMAGING DETECTOR COMPRISING THE SAME VIEWORKS CO LTD (KR) 2019-07-24 EP claimed
EP-2739210-B2 RADIATION IMAGING SYSTEM VIEWORKS CO LTD (KR) 2019-07-03 EP claimed
US-9459356-B2 Composition for radiation imaging detector and a radiation imaging detector comprising the same VIEWORKS CO., LTD. (KR) 2016-10-04 US claimed
EP-2739701-B1 A NOVEL COMPOSITION FOR RADIATION IMAGING DETECTOR AND A RADIATION IMAGING DETECTOR COMPRISING THE SAME VIEWORKS CO LTD (KR) 2016-02-10 EP claimed
EP-2739210-B1 RADIATION IMAGING SYSTEM VIEWORKS CO LTD (KR) 2016-02-10 EP claimed
US-8759781-B2 Radiation imaging system VIEWORKS CO., LTD. (KR) 2014-06-24 US claimed
EP-2739210-A2 RADIATION IMAGING SYSTEM Vieworks Co. Ltd. (KR) 2014-06-11 EP claimed
WO-2013019077-A2 RADIATION IMAGING SYSTEM VIEWORKS CO., LTD. (KR) 2013-02-07 WO claimed
US-20130032723-A1 RADIATION IMAGING SYSTEM VIEWORKS CO., LTD. (KR) 2013-02-07 US claimed
US-5989737-A Organic electroluminescent devices XEROX CORPORATION (US) 1999-11-23 US claimed
US-20190348619-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM SOLVAY SA (BE) 2019-11-14 US disclosed
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices POWER OLEDS LIMITED (GB) 2019-10-08 US disclosed
EP-2739701-B2 A NOVEL COMPOSITION FOR RADIATION IMAGING DETECTOR AND A RADIATION IMAGING DETECTOR COMPRISING THE SAME VIEWORKS CO LTD (KR) 2019-07-24 EP disclosed
EP-2739210-B2 RADIATION IMAGING SYSTEM VIEWORKS CO LTD (KR) 2019-07-03 EP disclosed
US-20190123283-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LIMITED (GB) 2019-04-25 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
EP-1898262-A1 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge Ricoh Company, Ltd. (JP) 2008-03-12 EP disclosed
US-5989737-A Organic electroluminescent devices XEROX CORPORATION (US) 1999-11-23 US disclosed
US-5891587-A ORGANIC ELECTROLUMINESCENT DEVICE COMPRISED OF ANODE, CATHODE, STARBURST AROMATIC AMINE COMPOUND XEROX CORPORATION (US) 1999-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190348619-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM AR, AHR, AXIN2 SIGMAR1 361/4885CYP1A2 370/4885CYP2A6 1099/4885
US-20190123283-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES OCIAD2, NUDT1, HTT SIGMAR1 1297/4885CYP1A2 895/4885CYP2A6 2042/4885
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices NAT1, SLCO2A1, SLCO2B1 SIGMAR1 402/4885CYP1A2 296/4885CYP2A6 1385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.