Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364218 | 0.90 | EP300 (0.48) | EP300HIF1AHDAC6MEN1KMT2A | |
| SCHEMBL8361728 | 0.88 | RORC (0.51) | HDAC6MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL8361739 | 0.88 | HDAC6 (0.46) | HDAC6MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL8363852 | 0.87 | ALOX15 (0.47) | HDAC6MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL8363828 | 0.86 | HDAC6 (0.44) | HDAC6MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL8364244 | 0.86 | HDAC6 (0.44) | HDAC6MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL8361730 | 0.86 | RORC (0.46) | HDAC6MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL8364249 | 0.85 | CNR1 (0.45) | HDAC6MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL8364256 | 0.85 | HDAC6 (0.46) | HDAC6MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL8363943 | 0.85 | KMT2A (0.44) | HDAC6MEN1KMT2AHDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013527-A1 | SULFONAMIDE DERIVATIVES AS GAMMA SECRETASE INHIBITORS | SCHERING CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |