Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366277 | 0.94 | MEN1 (0.49) | KDM1AMAOAMEN1KMT2ASLC16A3 | |
| SCHEMBL8697170 | 0.85 | MEN1 (0.56) | MEN1KMT2ASLC16A3HTR6MAPT | |
| SCHEMBL8366229 | 0.82 | AKR1C3 (0.53) | KDM1AMAOAMEN1KMT2AAKR1C3 | |
| SCHEMBL8364333 | 0.82 | AKR1C3 (0.53) | KDM1AMAOAMEN1KMT2AAKR1C3 | |
| SCHEMBL7322835 | 0.80 | MEN1 (0.58) | MEN1KMT2ASLC16A3MAPTAKR1C3 | |
| Hydrochloric Acid SCHEMBL8368784 | 0.80 | HTR6 (0.65) | RAB9AKDM1AMAOAMEN1KMT2A | |
| SCHEMBL8367822 | 0.79 | KDM1A (0.60) | KDM1AMAOAMEN1KMT2AHTR6 | |
| SCHEMBL7316591 | 0.78 | AKR1C3 (0.58) | KDM1AMAOAMEN1KMT2AAKR1C3 | |
| SCHEMBL7323404 | 0.78 | AKR1C3 (0.58) | KDM1AMAOAMEN1KMT2AAKR1C3 | |
| SCHEMBL25060949 | 0.77 | KCNA5 (0.61) | RAB9AMEN1KMT2ASLC16A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831800-A4 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-03-10 | — | — | EP | claimed |
| EP-0831800-A1 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040100-A1 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | claimed |