Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441494 | 0.87 | KMT2A (0.49) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL3450312 | 0.84 | POLB (0.56) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL8369776 | 0.82 | NPC1 (0.57) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL8368151 | 0.82 | MAPT (0.58) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL3448539 | 0.82 | MAPT (0.55) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL8366709 | 0.82 | RAB9A (0.57) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL1221564 | 0.82 | MEN1 (0.61) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL8589802 | 0.81 | KMT2A (0.59) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL8364912 | 0.79 | KMT2A (0.54) | L3MBTL1KMT2AMEN1MAPK1RAB9A | |
| SCHEMBL8369726 | 0.78 | KMT2A (0.53) | L3MBTL1KMT2AMEN1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |