Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | GAK | O14976 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | MARK1 | Q9P0L2 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450312 | 0.86 | POLB (0.56) | RAB9AKMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL8369776 | 0.85 | NPC1 (0.57) | RAB9AKMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL3448539 | 0.85 | MAPT (0.55) | RAB9AKMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL8368151 | 0.85 | MAPT (0.58) | RAB9AKMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL1221564 | 0.84 | MEN1 (0.61) | RAB9AKMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL3501972 | 0.84 | KMT2A (0.57) | RAB9AKMT2AL3MBTL1MAPK1AXL | |
| SCHEMBL8364912 | 0.84 | KMT2A (0.54) | RAB9AKMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL8589802 | 0.83 | KMT2A (0.59) | RAB9AKMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL8364669 | 0.82 | L3MBTL1 (0.52) | RAB9AKMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL70800 | 0.81 | RAB9A (0.55) | RAB9AKMT2AMEN1AXLKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945324-B | A kind of sulfenyl class compound and its application with antitumor activity | 沈阳药科大学 | 2017-06-13 | — | — | CN | disclosed |
| CN-104945324-A | Sulfur-based compound with anti-tumor activity and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-09-30 | — | — | CN | disclosed |
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |