Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023368 | 0.85 | KMT2A (0.57) | KMT2AMEN1L3MBTL1TNIKPOLB | |
| SCHEMBL8366709 | 0.84 | RAB9A (0.57) | KMT2AMEN1L3MBTL1MAPK1RAB9A | |
| SCHEMBL3450312 | 0.82 | POLB (0.56) | KMT2AMEN1L3MBTL1MAPK1RAB9A | |
| SCHEMBL8589802 | 0.82 | KMT2A (0.59) | KMT2AMEN1L3MBTL1MAPK1RAB9A | |
| SCHEMBL69008 | 0.82 | MEN1 (0.50) | KMT2AMEN1TNIKMAPK1KDR | |
| SCHEMBL7841174 | 0.82 | RAF1 (0.49) | TNIKMAPK1RAB9ANPC1POLB | |
| SCHEMBL3448539 | 0.81 | MAPT (0.55) | KMT2AMEN1L3MBTL1TNIKMAPK1 | |
| SCHEMBL8368151 | 0.81 | MAPT (0.58) | KMT2AMEN1L3MBTL1TNIKMAPK1 | |
| SCHEMBL8369776 | 0.81 | NPC1 (0.57) | KMT2AMEN1L3MBTL1TNIKMAPK1 | |
| SCHEMBL1221564 | 0.81 | MEN1 (0.61) | KMT2AMEN1L3MBTL1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |