Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744787 | 0.84 | ALPL (0.56) | ALPLKDM4ETARBP2POLBHTT | |
| SCHEMBL4872475 | 0.79 | ALPL (0.49) | ALPLKDM4ETARBP2POLBSMN1; SMN2 | |
| SCHEMBL6852749 | 0.79 | KDM4E (0.57) | KDM4ETARBP2POLBHTTMAPK10 | |
| SCHEMBL2197641 | 0.78 | ALOX5 (0.51) | KDM4ETARBP2POLBPTGESALOX5 | |
| SCHEMBL17803271 | 0.77 | MAPT (0.50) | KDM4ETARBP2POLBHTTMAPK10 | |
| SCHEMBL13883207 | 0.76 | NPSR1 (0.59) | ALPLPOLBL3MBTL1GABRA2GABRB2 | |
| SCHEMBL14152405 | 0.75 | TLR8 (0.47) | KDM4EPOLB | |
| SCHEMBL5023315 | 0.73 | ALPL (0.55) | ALPLKDM4ETARBP2POLBHTT | |
| SCHEMBL21331813 | 0.71 | KDM4E (0.55) | KDM4ETARBP2POLBHTTMAPK10 | |
| SCHEMBL8368083 | 0.70 | ALPL (0.52) | ALPLKDM4ETARBP2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |