Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172622 | 0.87 | KDM4E (0.56) | KDM4EPOLBTARBP2HPGDSALDH1A1 | |
| SCHEMBL21331813 | 0.86 | KDM4E (0.55) | KDM4EPOLBTARBP2HPGDSALDH1A1 | |
| SCHEMBL4744787 | 0.86 | ALPL (0.56) | KDM4EPOLBTARBP2GABRA2GABRB2 | |
| SCHEMBL20307754 | 0.85 | KDM4E (0.53) | KDM4EPOLBTARBP2HPGDSALDH1A1 | |
| SCHEMBL2197641 | 0.84 | ALOX5 (0.51) | KDM4EPOLBTARBP2HPGDSALDH1A1 | |
| SCHEMBL17803271 | 0.83 | MAPT (0.50) | KDM4EPOLBTARBP2ALDH1A1KMT2A | |
| SCHEMBL14152405 | 0.81 | TLR8 (0.47) | KDM4EPOLBHPGDSSLC34A1 | |
| SCHEMBL570062 | 0.81 | PIN1 (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11204630 | 0.80 | KDM4E (0.49) | KDM4EPOLBTARBP2HPGDSALDH1A1 | |
| SCHEMBL13539292 | 0.80 | SMN1; SMN2 (0.50) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324752-A | Five-membered heterocyclic compound with phenyl substitution, and preparation and application thereof | 江西中医药大学 | 2024-07-12 | — | — | CN | disclosed |
| US-8084467-B2 | For both CB1 and CB2 receptor sites; 3-(N-hetero)amido-5-phenyl pyrazoles; memory deficits associated with aging or nervous system disorders, obesity, schizophrenia, septic shock | UNIVERSITY OF CONNECTICUT (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084467-B2 | For both CB1 and CB2 receptor sites; 3-(N-hetero)amido-5-phenyl pyrazoles; memory deficits associated with aging or nervous system disorders, obesity, schizophrenia, septic shock | UNIVERSITY OF CONNECTICUT (US) | 2011-12-27 | — | — | US | disclosed |
| US-7745440-B2 | Pyrazole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2010-06-29 | — | — | US | disclosed |
| US-7745440-B2 | Pyrazole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2010-06-29 | — | — | US | disclosed |
| US-7393842-B2 | Pyrazole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2008-07-01 | — | — | US | disclosed |
| EP-1397360-A1 | AZAINDOLES | Aventis Pharma Limited (GB) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003000688-A1 | AZAINDOLES | AVENTIS PHARMA LIMITED (GB) | 2003-01-03 | — | — | WO | disclosed |
| EP-1263759-A2 | AZAINDOLES | Aventis Pharma Limited (GB) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001047922-A2 | AZAINDOLES | AVENTIS PHARMA LIMITED (GB) | 2001-07-05 | — | — | WO | disclosed |
| EP-0087780-A2 | Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1983-09-07 | — | — | EP | disclosed |