Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718975 | 0.94 | POLB (0.59) | HCAR2POLBGAAKDM4ENPC1 | |
| SCHEMBL8368711 | 0.90 | RAB9A (0.52) | HCAR2POLBGAAKDM4ENPC1 | |
| SCHEMBL6718898 | 0.88 | POLB (0.66) | HCAR2POLBGAAKDM4ENPC1 | |
| SCHEMBL19185049 | 0.76 | MEN1 (0.70) | HCAR2POLBGAAKDM4ENPC1 | |
| SCHEMBL6719405 | 0.75 | RAB9A (0.64) | HCAR2POLBGAAKDM4ENPC1 | |
| SCHEMBL10497116 | 0.73 | HCAR2 (0.78) | HCAR2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28316072 | 0.72 | ALDH1A1 (0.60) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8589705 | 0.72 | RAB9A (0.50) | HCAR2POLBGAAKDM4ENPC1 | |
| SCHEMBL6716874 | 0.71 | LMNA (0.67) | POLBGAAKDM4ENPC1RAB9A | |
| SCHEMBL8590044 | 0.71 | HDAC3 (0.47) | POLBKDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888322-A2 | ELECTROPHILIC KETONES FOR THE TREATMENT OF HERPESVIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034566-A2 | ELECTROPHILIC KETONES FOR THE TREATMENT OF HERPESVIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 1997-09-25 | — | — | WO | claimed |