Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719405 | 0.87 | RAB9A (0.64) | RAB9APOLBALDH1A1LMNATSHR | |
| SCHEMBL6718898 | 0.81 | POLB (0.66) | RAB9APOLBALDH1A1LMNATSHR | |
| SCHEMBL6717150 | 0.81 | MAPK1 (0.64) | RAB9AALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL6718796 | 0.79 | RAB9A (0.55) | RAB9AALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL8368711 | 0.79 | RAB9A (0.52) | RAB9APOLBALDH1A1KMT2AHCAR2 | |
| SCHEMBL6716874 | 0.72 | LMNA (0.67) | RAB9APOLBALDH1A1LMNAKMT2A | |
| SCHEMBL8365967 | 0.72 | HCAR2 (0.54) | RAB9APOLBALDH1A1LMNAKMT2A | |
| SCHEMBL5275083 | 0.71 | HDAC3 (0.48) | RAB9APOLBALDH1A1LMNAKMT2A | |
| SCHEMBL21701478 | 0.71 | CYP1A2 (0.61) | RAB9AALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL6716706 | 0.70 | RXFP1 (0.51) | RAB9AALDH1A1TSHRKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888322-A2 | ELECTROPHILIC KETONES FOR THE TREATMENT OF HERPESVIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034566-A2 | ELECTROPHILIC KETONES FOR THE TREATMENT OF HERPESVIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 1997-09-25 | — | — | WO | disclosed |