Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32691850 | 0.92 | GPR35 (0.64) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL1344484 | 0.92 | GPR35 (0.64) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL29382907 | 0.77 | VCAM1 (0.56) | GPR35ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL56638 | 0.77 | VCAM1 (0.56) | GPR35ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5682648 | 0.76 | GPR35 (0.67) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| Selenium SCHEMBL9501261 | 0.76 | VCAM1 (0.55) | GPR35ALDH1A1MEN1KMT2AMAPT | |
| Phenol SCHEMBL28138934 | 0.76 | VCAM1 (0.47) | GPR35ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL70167 | 0.75 | GPR35 (0.78) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL29392995 | 0.75 | — | — | |
| SCHEMBL5756 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948330-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0948330-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998005328-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-12 | — | — | WO | disclosed |