Sugi Predict

Sugi Predict / Compounds / SCHEMBL1344484

SCHEMBL1344484

SCHEMBL1344484

N#Cc1cccc([N+](=O)[O-])c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR35 Q9HC97 2/20 0.64
▸ ERN1 O75460 1/20 0.51
▸ VCAM1 P19320 1/20 0.46
▸ TDP1 Q9NUW8 3/20 0.45
▸ ALDH1A1 P00352 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ CTSB P07858 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ CXCR1 P25024 1/20 0.42
▸ CXCR2 P25025 1/20 0.42
▸ MAPT P10636 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ GLA P06280 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32691850 1.00 GPR35 (0.64) GPR35ERN1VCAM1TDP1ALDH1A1
SCHEMBL8366183 0.92 GPR35 (0.55) GPR35ERN1VCAM1TDP1ALDH1A1
SCHEMBL5682648 0.83 GPR35 (0.67) GPR35ERN1TDP1ALDH1A1HPGD
SCHEMBL29382907 0.80 VCAM1 (0.56) GPR35VCAM1TDP1ALDH1A1HPGD
SCHEMBL56638 0.80 VCAM1 (0.56) GPR35VCAM1TDP1ALDH1A1HPGD
SCHEMBL1077970 0.80 GPR35 (1.00) GPR35ERN1TDP1ALDH1A1L3MBTL1
SCHEMBL30694393 0.79 VCAM1 (0.47) GPR35VCAM1TDP1ALDH1A1HPGD
SCHEMBL622040 0.79 GPR35 (0.53) GPR35VCAM1TDP1ALDH1A1HPGD
SCHEMBL220318 0.79 VCAM1 (0.47) GPR35VCAM1TDP1ALDH1A1HPGD
Phenol SCHEMBL28138934 0.79 VCAM1 (0.47) GPR35VCAM1TDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264850-A Pressure-resistant and deformation-resistant plywood and preparation method thereof 江苏万木春木业有限公司 2025-01-07 — — CN claimed
CN-118184591-A Preparation method of 2-methoxy-3- (1-methyl-1H-1, 2, 4-triazole-3-yl) aniline 上海工程技术大学 2024-06-14 — — CN claimed
US-20250333416-A1 PROCESS FOR MAKING A PD-1/PD-L1 INHIBITOR AND SALTS AND CRYSTALLINE FORMS THEREOF INCYTE CORP (US) 2025-10-30 — — US disclosed
EP-4638442-A1 TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS Uniquest Pty Limited (AU) 2025-10-29 — — EP disclosed
US-12404272-B2 Process for making a PD-1/PD-L1 inhibitor and salts and crystalline forms thereof INCYTE CORPORATION (US) 2025-09-02 — — US disclosed
US-20250243193-A1 AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES SYNGENE INTERNATIONAL LIMITED (IN) 2025-07-31 — — US disclosed
CN-119264850-A Pressure-resistant and deformation-resistant plywood and preparation method thereof 江苏万木春木业有限公司 2025-01-07 — — CN disclosed
CN-119264850-A Pressure-resistant and deformation-resistant plywood and preparation method thereof 江苏万木春木业有限公司 2025-01-07 — — CN disclosed
US-20240376106-A1 PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION 2024-11-14 — — US disclosed
US-12084443-B2 Process of preparing a PD-1/PD-L1 inhibitor INCYTE CORPORATION (US) 2024-09-10 — — US disclosed
WO-2024130342-A1 TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS UNIQUEST PTY LIMITED (AU) 2024-06-27 — — WO disclosed
CN-1215990-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORP (US) 1999-05-05 — — CN disclosed
US-5886044-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1999-03-23 — — US disclosed
EP-0896531-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1999-02-17 — — EP disclosed
US-5780483-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1998-07-14 — — US disclosed
WO-1998005317-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1998-02-12 — — WO disclosed
WO-1997049286-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-12-31 — — WO disclosed
EP-0809492-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-12-03 — — EP disclosed
WO-1997029743-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-08-21 — — WO disclosed
WO-1996025157-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1996-08-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376106-A1 PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR PDCD1, CD274, PDCD1LG2 GPR35 4658/4885ERN1 1764/4885VCAM1 173/4885
US-20250243193-A1 AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES IFNG, IFNAR1, TYK2 GPR35 1270/4885ERN1 673/4885VCAM1 3861/4885
US-12084443-B2 Process of preparing a PD-1/PD-L1 inhibitor PDCD1, CD274, PDCD1LG2 GPR35 4658/4885ERN1 1764/4885VCAM1 173/4885
US-12404272-B2 Process for making a PD-1/PD-L1 inhibitor and salts and crystalline forms thereof CD274, PDCD1, PDCD1LG2 GPR35 4572/4885ERN1 1920/4885VCAM1 121/4885
US-20250333416-A1 PROCESS FOR MAKING A PD-1/PD-L1 INHIBITOR AND SALTS AND CRYSTALLINE FORMS THEREOF CD274, PDCD1, PDCD1LG2 GPR35 4572/4885ERN1 1920/4885VCAM1 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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