Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366389 | 0.79 | CTSD (0.45) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL8711005 | 0.78 | POLB (0.60) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8368080 | 0.78 | FAAH (0.43) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8366393 | 0.77 | NOTUM (0.41) | ALDH1A1MAOBPOLBNPC1RAB9A | |
| SCHEMBL3028929 | 0.75 | NPC1 (0.54) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9872943 | 0.75 | POLB (0.71) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8708189 | 0.74 | POLB (0.57) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| Imidazole SCHEMBL9873212 | 0.72 | POLB (0.48) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10489859 | 0.71 | KDM4E (0.60) | KDM4EALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL9873218 | 0.70 | POLB (0.48) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929089-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |