Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 11/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366392 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1NOTUMMEN1KMT2A | |
| SCHEMBL8366389 | 0.73 | CTSD (0.45) | KDM4EALDH1A1HSD17B10NOTUMHPGD | |
| SCHEMBL8308838 | 0.73 | DRD4 (0.38) | ALDH1A1TDP1HPGDSTAT3 | |
| SCHEMBL7799616 | 0.71 | HTR4 (0.36) | ALDH1A1TDP1HPGDMEN1LMNA | |
| SCHEMBL6958303 | 0.71 | DRD4 (0.41) | ALDH1A1TDP1HPGDSTAT3 | |
| SCHEMBL8307501 | 0.71 | GPR55 (0.39) | KMT2ANPSR1LRRK2 | |
| SCHEMBL7799610 | 0.70 | HTR4 (0.38) | ALDH1A1HPGDMEN1KMT2ASTAT3 | |
| SCHEMBL6961012 | 0.70 | NOTUM (0.44) | NOTUM | |
| SCHEMBL18394492 | 0.66 | ALDH1A1 (0.68) | KDM4EALDH1A1HSD17B10GLANOTUM | |
| SCHEMBL29664535 | 0.66 | ALDH1A1 (0.68) | KDM4EALDH1A1HSD17B10GLANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980368-B1 | 3-(PYRROLIDIN-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AND THEIR USE AS 5-HT4 LIGANDS | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| EP-0975631-B1 | 5-ARYL-3-(8-AZABICYCLO[3.2.1]OCT-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AS 5-HT4 RECEPTOR LIGANDS | SANOFI SYNTHELABO (FR) | 2001-10-04 | — | — | EP | disclosed |
| US-6255319-B1 | ANTISEROTONIN AGENT | SANOFI-SYNTHELABO (FR) | 2001-07-03 | — | — | US | disclosed |
| US-6248757-B1 | ANTISEROTONINE AGENTS | SANOFI-SYNTHELABO (FR) | 2001-06-19 | — | — | US | disclosed |
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |