Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8151433 | 0.98 | TLR8 (0.36) | ADORA2AADORA2BALDH1A1KMT2APOLB | |
| SCHEMBL17581662 | 0.88 | CYP1A2 (0.37) | ALDH1A1KMT2APOLBMAPK1MEN1 | |
| SCHEMBL13587988 | 0.88 | TLR8 (0.39) | ADORA2AADORA2BALDH1A1KMT2APOLB | |
| SCHEMBL9866983 | 0.86 | ADORA2A (0.33) | ADORA2AADORA2BALDH1A1KMT2APOLB | |
| SCHEMBL9866166 | 0.84 | ALDH1A1 (0.36) | ADORA2AADORA2BALDH1A1KMT2APOLB | |
| SCHEMBL9866879 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHR | |
| SCHEMBL9867208 | 0.82 | SIGMAR1 (0.34) | ADORA2AADORA2BALDH1A1KMT2APOLB | |
| SCHEMBL9867170 | 0.82 | ALDH1A1 (0.38) | ADORA2AADORA2BALDH1A1KMT2APOLB | |
| SCHEMBL9866875 | 0.82 | ADORA2A (0.34) | ADORA2AADORA2BALDH1A1KMT2APOLB | |
| SCHEMBL9866841 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888308-A1 | PROCESS FOR PREPARING HETEROCYCLIC CARBENES | Celanese GmbH (DE) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034875-A1 | PROCESS FOR PREPARING HETEROCYCLIC CARBENES | CELANESE GMBH (DE) | 1997-09-25 | — | — | WO | disclosed |