Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866879 | 0.99 | ALDH1A1 (0.42) | ALDH1A1TSHRL3MBTL1HRH3MAOB | |
| SCHEMBL9866807 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TSHRHRH3KCNH2KDM4E | |
| SCHEMBL9867651 | 0.85 | PKM (0.44) | ALDH1A1TSHRL3MBTL1HRH3KDM4E | |
| SCHEMBL8367322 | 0.81 | ADORA2A (0.36) | ALDH1A1TSHRKCNH2 | |
| Hydrochloric Acid SCHEMBL8151433 | 0.80 | TLR8 (0.36) | ALDH1A1TSHRKCNH2 | |
| SCHEMBL9866166 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HRH3KCNH2KDM4E | |
| SCHEMBL9867208 | 0.77 | SIGMAR1 (0.34) | ALDH1A1HRH3KDM4E | |
| SCHEMBL9867170 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HRH3KCNH2KDM4E | |
| SCHEMBL13587988 | 0.77 | TLR8 (0.39) | ALDH1A1TSHRKCNH2 | |
| SCHEMBL9866859 | 0.76 | ALDH1A1 (0.37) | ALDH1A1HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011838-A | Antiallergens, antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-04-30 | — | — | US | disclosed |
| EP-0397615-A2 | Pharmacologically active 2-substituted 3-(2-ethoxyethyl) imidazo [4,5-b] pyridines and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |