Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 9/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516665 | 0.83 | HCRTR1 (0.46) | KCNA5PPARGPPARAMEN1NPC1 | |
| SCHEMBL8369053 | 0.82 | NR1H4 (0.53) | KCNA5PPARGPPARAMEN1NPC1 | |
| SCHEMBL8369813 | 0.72 | DHODH (0.44) | KCNA5PPARGPPARAMEN1NPC1 | |
| SCHEMBL8516703 | 0.70 | PPARG (0.45) | PPARGPPARAMEN1NPC1RAB9A | |
| SCHEMBL7801348 | 0.69 | PPARG (0.68) | PPARGPPARANPC1RAB9A | |
| SCHEMBL8517477 | 0.69 | PPARG (0.43) | PPARGPPARAMEN1RAB9AKMT2A | |
| SCHEMBL7799996 | 0.68 | PPARA (0.89) | PPARGPPARANPC1RAB9A | |
| SCHEMBL22109001 | 0.67 | PPARG (0.56) | PPARGPPARAMEN1NPC1RAB9A | |
| SCHEMBL8369877 | 0.66 | RAB9A (0.44) | KCNA5MEN1NPC1RAB9AKMT2A | |
| SCHEMBL16088691 | 0.65 | KMT2A (0.61) | PPARGPPARAMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | disclosed |