Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 9/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367446 | 0.83 | KCNA5 (0.48) | MEN1NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL8370053 | 0.83 | DHODH (0.54) | HCRTR1HCRTR2MEN1NPC1RAB9A | |
| SCHEMBL8517477 | 0.70 | PPARG (0.43) | MEN1RAB9AKMT2APPARGPPARA | |
| SCHEMBL8516703 | 0.68 | PPARG (0.45) | MEN1NPC1RAB9AKMT2APPARG | |
| SCHEMBL7801348 | 0.68 | PPARG (0.68) | NPC1RAB9APPARGPPARASMN1; SMN2 | |
| SCHEMBL8369027 | 0.67 | NPC1 (0.46) | MEN1NPC1RAB9AKMT2ADHODH | |
| SCHEMBL7799996 | 0.66 | PPARA (0.89) | NPC1RAB9APPARGPPARASMN1; SMN2 | |
| SCHEMBL11000139 | 0.65 | CTSD (0.46) | PPARGPPARAHTT | |
| SCHEMBL8369053 | 0.64 | NR1H4 (0.53) | MEN1NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL10607832 | 0.64 | ACHE (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | disclosed |