Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8364701 | 0.85 | CYP2D6 (0.38) | — | |
| SCHEMBL27949026 | 0.74 | PTGS2 (0.42) | PDE4B | |
| Hydrochloric Acid SCHEMBL7458205 | 0.73 | PDE4B (0.31) | PDE4B | |
| Hydrochloric Acid SCHEMBL9066149 | 0.72 | CFTR (0.40) | — | |
| SCHEMBL6673694 | 0.72 | PTGS2 (0.38) | — | |
| SCHEMBL20722299 | 0.69 | ALDH1A1 (0.42) | PDE4B | |
| Hydrochloric Acid SCHEMBL8468727 | 0.69 | PDE4B (0.31) | PDE4B | |
| Hydrochloric Acid SCHEMBL6286926 | 0.69 | CFTR (0.38) | — | |
| Hydrochloric Acid SCHEMBL7869757 | 0.69 | CALM1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL618163 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999035171-A1 | HIGH-MELTING POLYOLEFIN COPOLYMER ELASTOMERS, CATALYSTS AND METHODS OF SYNTHESIS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) | 1999-07-15 | — | — | WO | disclosed |