Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950868 | 0.92 | TSHR (0.53) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL19552359 | 0.88 | TSHR (0.45) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL19552813 | 0.87 | TSHR (0.48) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL19552658 | 0.83 | TSHR (0.55) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL19552660 | 0.83 | TSHR (0.55) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL14700651 | 0.80 | TSHR (0.57) | TSHRHPGDATMALDH1A1HCAR2 | |
| Acrylic Acid SCHEMBL31675161 | 0.79 | TSHR (0.56) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL835605 | 0.79 | — | — | |
| SCHEMBL27553925 | 0.78 | TSHR (0.55) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL22281529 | 0.78 | TSHR (0.55) | TSHRHPGDATMALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745375-B2 | Adipate-type compounds and a process of preparing it | HALDOR TOPSØE A/S (DK) | 2020-08-18 | — | — | US | disclosed |
| US-20200115359-A1 | NEW ADIPATE-TYPE COMPOUNDS AND A PROCESS OF PREPARING IT | HALDOR TOPSØE A/S (DK) | 2020-04-16 | — | — | US | disclosed |
| US-20190144415-A1 | NEW ADIPATE-TYPE COMPOUNDS AND A PROCESS OF PREPARING IT | HALDOR TOPSØE A/S (DK) | 2019-05-16 | — | — | US | disclosed |
| EP-3452459-A1 | NEW ADIPATE-TYPE COMPOUNDS AND A PROCESS OF PREPARING IT | Haldor Topsøe A/S (DK) | 2019-03-13 | — | — | EP | disclosed |
| WO-2017191282-A1 | NEW ADIPATE-TYPE COMPOUNDS AND A PROCESS OF PREPARING IT | HALDOR TOPSØE A/S (DK) | 2017-11-09 | — | — | WO | disclosed |
| EP-2184270-B1 | Zeolite-catalyzed preparation of alpha-hydroxy carboxylic acid compounds and esters thereof | HALDOR TOPSOE AS (DK) | 2013-02-13 | — | — | EP | disclosed |
| US-8143439-B2 | Zeolite-catalyzed preparation of alpha-hydroxy carboxylic acids and esters thereof | HALDOR TOPSØE A/S (DK) | 2012-03-27 | — | — | US | disclosed |
| US-20100121096-A1 | ZEOLITE-CATALYZED PREPARATION OF ALPHA-HYDROXY CARBOXYLIC ACIDS AND ESTERS THEREOF | TOPSOE A/S (DK) | 2010-05-13 | — | — | US | disclosed |
| EP-2184270-A1 | Zeolite-catalyzed preparation of alpha-hydroxy carboxylic acid compounds and esters thereof | Haldor Topsoe A/S (DK) | 2010-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144415-A1 | NEW ADIPATE-TYPE COMPOUNDS AND A PROCESS OF PREPARING IT | ADIPOR1, FABP4, ADIPOR2 | TSHR 4531/4885HPGD 617/4885ATM 2943/4885 |
| US-10745375-B2 | Adipate-type compounds and a process of preparing it | ADIPOR1, FABP4, ADIPOR2 | TSHR 4519/4885HPGD 613/4885ATM 2087/4885 |
| US-20100121096-A1 | ZEOLITE-CATALYZED PREPARATION OF ALPHA-HYDROXY CARBOXYLIC ACIDS AND ESTERS THEREOF | LDHA, HAO2, ALDOA | TSHR 3225/4885HPGD 388/4885ATM 4547/4885 |
| US-20200115359-A1 | NEW ADIPATE-TYPE COMPOUNDS AND A PROCESS OF PREPARING IT | ADIPOR1, FABP4, ADIPOR2 | TSHR 4498/4885HPGD 634/4885ATM 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.