Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD4 | P21917 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | FPR3 | P25089 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arbutamine SCHEMBL7870502 | 0.88 | ADRB2 (0.58) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Arbutamine SCHEMBL29390265 | 0.84 | ADRB2 (0.61) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Arbutamine SCHEMBL521645 | 0.84 | ADRB2 (0.61) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Arbutamine SCHEMBL3699485 | 0.84 | ADRB2 (0.61) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Arbutamine SCHEMBL20769823 | 0.84 | ADRB2 (0.61) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Arbutamine SCHEMBL29929016 | 0.84 | ADRB2 (0.61) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Arbutamine SCHEMBL7295080 | 0.83 | ADRB2 (0.60) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Arbutamine SCHEMBL40757 | 0.83 | ADRB2 (0.60) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Arbutamine SCHEMBL4327619 | 0.82 | ADRB2 (0.59) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| SCHEMBL10477708 | 0.79 | ADRB2 (0.80) | ADRB2ADRB1ADRB3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874601-A | Process of protecting a 1,2-aminoalcohol for reductive amination coupling | ABBOTT LABORATORIES (US) | 1999-02-23 | — | — | US | claimed |
| EP-0888282-A1 | PROCESS OF PROTECTING A 1,2-AMINOALCOHOL FOR REDUCTIVE AMINATION COUPLING | Abbott Laboratories (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997033857-A1 | PROCESS OF PROTECTING A 1,2-AMINOALCOHOL FOR REDUCTIVE AMINATION COUPLING | ABBOTT LABORATORIES (US) | 1997-09-18 | — | — | WO | claimed |
| US-5874601-A | Process of protecting a 1,2-aminoalcohol for reductive amination coupling | ABBOTT LABORATORIES (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0888282-A1 | PROCESS OF PROTECTING A 1,2-AMINOALCOHOL FOR REDUCTIVE AMINATION COUPLING | Abbott Laboratories (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997033857-A1 | PROCESS OF PROTECTING A 1,2-AMINOALCOHOL FOR REDUCTIVE AMINATION COUPLING | ABBOTT LABORATORIES (US) | 1997-09-18 | — | — | WO | disclosed |