Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809439 | 0.80 | ALDH1A1 (0.39) | SRCALDH1A1ACP3ANPEPOPRD1 | |
| SCHEMBL5425825 | 0.79 | LMNA (0.42) | CYP1A2MEN1KMT2AOPRD1CYP2D6 | |
| SCHEMBL1810262 | 0.75 | ACP3 (0.45) | ACP3ANPEPPKMSMN1; SMN2 | |
| SCHEMBL27747247 | 0.72 | CYP2C19 (0.42) | CYP1A2KMT2ACYP2D6PKMSMN1; SMN2 | |
| SCHEMBL16468978 | 0.71 | MMP2 (0.44) | ALDH1A1OPRD1 | |
| SCHEMBL28542544 | 0.71 | PTGS2 (0.45) | CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL7717083 | 0.70 | SRC (0.41) | SRCACP3ANPEP | |
| SCHEMBL1811461 | 0.69 | CYP1A2 (0.39) | CYP1A2MEN1KMT2ACYP2D6SMN1; SMN2 | |
| SCHEMBL1811752 | 0.69 | CYP1A2 (0.41) | SRCALDH1A1ACP3ANPEPCYP1A2 | |
| SCHEMBL1806980 | 0.69 | PPARG (0.45) | ACP3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999064156-A1 | LONG-LIVED HOMOGENOUS AMIDE CONTAINING MACROCYCLIC COMPOUNDS | CARNEGIE MELLON UNIVERSITY (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999064563-A1 | POLYMER CARRIER FOR CULTIVATION OF KERATINOCYTES | ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) | 1999-12-16 | — | — | WO | disclosed |