Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 10/20 | 0.35 |
| ▸ | PRKCB | P05771 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656323 | 0.85 | CAMK2D (0.36) | GSK3BCAMK2DPRKCBPIM1USP2 | |
| SCHEMBL7659483 | 0.84 | CAMK2D (0.39) | GSK3BCAMK2DPIM1CNR2USP2 | |
| SCHEMBL8368712 | 0.84 | CAMK2D (0.33) | GSK3BCAMK2DPIM1USP2ALDH1A1 | |
| SCHEMBL8366859 | 0.83 | CAMK2D (0.33) | GSK3BCAMK2DPIM1USP2ALDH1A1 | |
| SCHEMBL8368564 | 0.83 | CAMK2D (0.36) | GSK3BCAMK2DUSP2ALDH1A1CYP1A2 | |
| SCHEMBL7664679 | 0.81 | CAMK2D (0.32) | CAMK2D | |
| SCHEMBL8365231 | 0.80 | CNR2 (0.37) | CAMK2DCNR2 | |
| SCHEMBL8516363 | 0.80 | MAPT (0.36) | CNR2ALDH1A1 | |
| SCHEMBL8516997 | 0.79 | ASH1L (0.37) | GSK3BCAMK2D | |
| Acetic Acid SCHEMBL8516677 | 0.78 | GSK3B (0.41) | GSK3BCAMK2DPRKCBPRKCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |