Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 9/20 | 0.65 |
| ▸ | PPP1CA | P62136 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728116 | 0.89 | SMPD1 (0.64) | RPA1PPP1CASMN1; SMN2SMPD1PTGS2 | |
| SCHEMBL877377 | 0.83 | SMPD1 (0.58) | RPA1PPP1CASMN1; SMN2SMPD1PTGS2 | |
| SCHEMBL16797379 | 0.82 | KDM1A (0.60) | RPA1PPP1CASMN1; SMN2SMPD1PTGS2 | |
| SCHEMBL4011074 | 0.81 | RPA1 (0.65) | RPA1PPP1CACA9 | |
| SCHEMBL3866686 | 0.81 | SMPD1 (0.56) | RPA1PPP1CASMN1; SMN2SMPD1PTGS2 | |
| SCHEMBL28038232 | 0.80 | BCL2 (0.65) | RPA1PPP1CASMN1; SMN2SMPD1PTGS2 | |
| SCHEMBL3863977 | 0.80 | PTGS2 (0.66) | PPP1CASMN1; SMN2SMPD1PTGS2CA9 | |
| SCHEMBL861458 | 0.80 | SMPD1 (0.55) | RPA1PPP1CASMN1; SMN2SMPD1PTGS2 | |
| SCHEMBL13290381 | 0.80 | PTGS2 (0.66) | PPP1CASMN1; SMN2SMPD1PTGS2CA9 | |
| SCHEMBL25221707 | 0.80 | NOTUM (0.56) | RPA1PPP1CASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |