Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.56 |
| ▸ | CTSB | P07858 | 8/20 | 0.56 |
| ▸ | CTSS | P25774 | 13/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSH | P09668 | 1/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360722 | 0.90 | CTSL (0.56) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7414183 | 0.78 | CTSL (0.59) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7400251 | 0.78 | CTSL (0.73) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7400248 | 0.78 | CTSL (0.73) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7400246 | 0.78 | CTSL (0.73) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL6449419 | 0.76 | CTSB (0.67) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL8696030 | 0.75 | CTSL (0.70) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7414216 | 0.75 | CTSL (0.70) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL8696034 | 0.75 | CTSL (0.70) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7414213 | 0.75 | CTSL (0.70) | CTSLCTSBCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756625-A4 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARM CORP (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0756625-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-02-05 | — | — | EP | disclosed |