Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | GPX4 | P36969 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837035 | 1.00 | NPC1 (0.47) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL835337 | 0.95 | MEN1 (0.43) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL835336 | 0.95 | MEN1 (0.43) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL27571662 | 0.93 | NPC1 (0.41) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL27571661 | 0.90 | MEN1 (0.43) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL3191188 | 0.87 | MEN1 (0.39) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL1705232 | 0.87 | MEN1 (0.39) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL1248768 | 0.85 | MEN1 (0.39) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL2163503 | 0.85 | MEN1 (0.39) | NPC1RAB9APAX8JAK2MEN1 | |
| SCHEMBL7761053 | 0.85 | NPC1 (0.36) | NPC1RAB9APAX8JAK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174446-B1 | A METHOD OF MANUAL SURFACE CLEANING USING CLEANING TEXTILES AND OF WASHING SAID CLEANING TEXTILES | ECOLAB USA INC (US) | 2019-01-30 | — | — | EP | disclosed |
| US-20170209016-A1 | METHOD OF MANUAL SURFACE CLEANING USING CLEANING TEXTILES AND OF WASHING SAID CLEANING TEXTILES | ECOLAB USA INC. | 2017-07-27 | — | — | US | disclosed |
| EP-3174446-A1 | A METHOD OF MANUAL SURFACE CLEANING USING CLEANING TEXTILES AND OF WASHING SAID CLEANING TEXTILES | Ecolab USA Inc. (US) | 2017-06-07 | — | — | EP | disclosed |
| EP-3083916-A1 | DISINFECTANT COMPOSITION WITH EXCELLENT FOAM PROFILE AND CLEANING POWER | Henkel AG & Co. KGaA (DE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015091164-A1 | DISINFECTANT COMPOSITION WITH EXCELLENT FOAM PROFILE AND CLEANING POWER | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015091163-A1 | DISINFECTANT COMPOSITION WITH EXCELLENT FOAM PROFILE | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | disclosed |
| US-8143207-B2 | Biocidal textile treatment agent | HENKEL AG & CO. KGAA (DE) | 2012-03-27 | — | — | US | disclosed |
| US-7985570-B2 | Alkaline proteases and detergents and cleaners comprising these alkaline proteases | B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK A.G. (DE) | 2011-07-26 | — | — | US | disclosed |
| US-20100298198-A1 | Alkaline Proteases and Detergents and Cleaners Comprising These Alkaline Proteases | HENKEL KGAA (DE) | 2010-11-25 | — | — | US | disclosed |
| US-7807616-B2 | Geranonitrile substitute | HENKEL AG & CO. KGAA (DE) | 2010-10-05 | — | — | US | disclosed |
| US-20050113273-A1 | Alkaline protease from bacillus gibsonii (DSM 14393) and washing and cleaning products comprising said alkaline protease | HENKEL AG & CO. KGAA (DE) | 2005-05-26 | — | — | US | disclosed |
| US-20050043198-A1 | Alkaline protease from Bacillus sp. (DSM 14392) and washing and cleaning products comprising said alkaline protease | HENKEL AG & CO. KGAA (DE) | 2005-02-24 | — | — | US | disclosed |
| US-20050009167-A1 | Alkaline protease from Bacillus sp. (DSM 14390) and washing and cleaning products comprising said alkaline protease | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-01-13 | — | — | US | disclosed |
| US-20050003504-A1 | Alkaline protease from Bacillus gibsonii (DSM 14391) and washing and cleaning products comprising said alkaline protease | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-01-06 | — | — | US | disclosed |
| US-20050003985-A1 | Alkaline protease variants | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-01-06 | — | — | US | disclosed |
| US-20050003419-A1 | Glycosyl hydrolases | B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (DE) | 2005-01-06 | — | — | US | disclosed |
| US-20040087475-A1 | Quaternary ammonium softener, polyethersiloxane spreading agent and silicone oil ironability enhancer; textile laundering; nonstaining | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-05-06 | — | — | US | disclosed |
| US-20040031107-A1 | Cleaning material | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL HGAA) (DE) | 2004-02-19 | — | — | US | disclosed |
| US-6569344-B1 | Fabrics; water soluble wetting agent and a salt | THE PROCTER & GAMBLE COMPANY | 2003-05-27 | — | — | US | disclosed |
| US-20010031714-A1 | Laundry, dishwashing or cleaning product detergent portions with controlled release of active substance | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009167-A1 | Alkaline protease from Bacillus sp. (DSM 14390) and washing and cleaning products comprising said alkaline protease | ANPEP, TMPRSS15, RNPEP | NPC1 3835/4885RAB9A 3106/4885PAX8 4225/4885 |
| US-20050043198-A1 | Alkaline protease from Bacillus sp. (DSM 14392) and washing and cleaning products comprising said alkaline protease | ANPEP, RNPEP, TMPRSS15 | NPC1 3953/4885RAB9A 3414/4885PAX8 4004/4885 |
| US-20050003419-A1 | Glycosyl hydrolases | AGL, ENGASE, UNG | NPC1 1625/4885RAB9A 3339/4885PAX8 4324/4885 |
| US-20050113273-A1 | Alkaline protease from bacillus gibsonii (DSM 14393) and washing and cleaning products comprising said alkaline protease | PRSS2, ALPI, GBA3 | NPC1 4181/4885RAB9A 2921/4885PAX8 4243/4885 |
| US-20050003504-A1 | Alkaline protease from Bacillus gibsonii (DSM 14391) and washing and cleaning products comprising said alkaline protease | ALPI, RNPEP, PRSS2 | NPC1 4112/4885RAB9A 2325/4885PAX8 4303/4885 |
| US-20050003985-A1 | Alkaline protease variants | LCT, TMPRSS11D, CTRL | NPC1 3578/4885RAB9A 971/4885PAX8 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.