Sugi Predict

Sugi Predict / Compounds / SCHEMBL1705232

SCHEMBL1705232

SCHEMBL1705232

CCCCN=C(NC(=N)N)N(CCCN(C(=N)NC(=N)N)c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ ADRB2 P07550 1/20 0.38
▸ NPC1 O15118 1/20 0.36
▸ JAK2 O60674 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ PAX8 Q06710 1/20 0.36
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ SCN5A Q14524 2/20 0.33
▸ SCN2A Q99250 2/20 0.33
▸ TP53 P04637 1/20 0.33
▸ MAPT P10636 1/20 0.31
▸ ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3191188 1.00 MEN1 (0.39) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL2163503 0.96 MEN1 (0.39) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL1248768 0.96 MEN1 (0.39) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL27571661 0.92 MEN1 (0.43) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL835336 0.89 MEN1 (0.43) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL835337 0.89 MEN1 (0.43) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL837035 0.87 NPC1 (0.47) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL837034 0.87 NPC1 (0.47) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL27571662 0.87 NPC1 (0.41) MEN1KMT2AALDH1A1ADRB2NPC1
SCHEMBL7009170 0.85 NPC1 (0.44) MEN1KMT2AALDH1A1ADRB2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580549-B2 Esterases for separating plastics HENKEL KGAA (DE) 2013-11-12 — — US disclosed
EP-1238054-B2 WASHING AGENT, RINSING AGENT OR CLEANING AGENT PORTIONS WITH ENZYME-CONTROLLED ACTIVE INGREDIENT RELEASE HENKEL AG & CO KGAA (DE) 2012-06-20 — — EP disclosed
EP-2097059-B1 CLEANSING OR CARE PRODUCT HENKEL KGAA (DE) 2012-04-18 — — EP disclosed
US-20100330013-A1 AMADORIASES IN WASHING AND CLEANING PRODUCTS HENKEL AG & CO. KGAA (DE) 2010-12-30 — — US disclosed
US-7811076-B2 Alkaline protease and washing and cleaning products containing said novel alkaline protease HENKEL AG & CO. KGAA (DE) 2010-10-12 — — US disclosed
US-7803604-B2 Amylolytic enzyme extracted from Bacillus sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme HENKEL AG & CO. KGAA (DE) 2010-09-28 — — US disclosed
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES BROADLEY KENNETH N 2010-02-11 — — US disclosed
US-20100029978-A1 RAPIDLY CURING CYANOACRYLATES AS ADHESIVES SWORDS NOELEEN 2010-02-04 — — US disclosed
US-20090275493-A1 Novel Alkaline Protease from Bacillus Gibsonii and Washing and Cleaning Agents containing said Novel Alkaline Protease HENKEL AG & CO. KGAA (DE) 2009-11-05 — — US disclosed
US-20090258406-A1 Use of esterases for separating plastics HENKEL KGAA (DE) 2009-10-15 — — US disclosed
US-6689223-B1 CLEANING SURFACES USING STORAGE STABLE LIQUID DETERGENTS HAVING INTERFACES WHICH CAN BE EMULSIFIED BY AGITATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-02-10 — — US disclosed
US-20030162689-A1 Conditioning preparation for fabric care HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-08-28 — — US disclosed
WO-2003004593-A1 MULTI-PHASE DETERGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-01-16 — — WO disclosed
US-6432892-B2 WITH ALKYL POLYGLYCOSIDE NONIONIC SURFACTANTS; CLEAR, LOW-FOAMING HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-08-13 — — US disclosed
EP-1214393-A1 MULTI-PHASE CLEANING AGENT WITH ANTI-MICROBIAL ACTION Henkel Kommanditgesellschaft auf Aktien (DE) 2002-06-19 — — EP disclosed
US-20010056047-A1 Cleaning of fruit, vegetables, and meats HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2001-12-27 — — US disclosed
WO-2001085897-A9 CONCENTRATE CONTAINING SURFACTANTS HENKEL KGAA (DE) 2001-12-27 — — WO disclosed
WO-2001085896-A1 CONCENTRATE FOR DILUTION WITH MAINTENANCE OF OR AN INCREASE IN VISCOSITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-11-15 — — WO disclosed
US-20010031714-A1 Laundry, dishwashing or cleaning product detergent portions with controlled release of active substance HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2001-10-18 — — US disclosed
WO-2001021755-A1 MULTI-PHASE CLEANING AGENT WITH ANTI-MICROBIAL ACTION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-03-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275493-A1 Novel Alkaline Protease from Bacillus Gibsonii and Washing and Cleaning Agents containing said Novel Alkaline Protease PRSS2, CPB2, GBA3 MEN1 2492/4885KMT2A 2610/4885ALDH1A1 3820/4885
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES KIT, TEKT1, CUTA MEN1 2598/4885KMT2A 1310/4885ALDH1A1 740/4885
US-20100029978-A1 RAPIDLY CURING CYANOACRYLATES AS ADHESIVES ICAM1, ITGA1, ITGA5 MEN1 3254/4885KMT2A 943/4885ALDH1A1 386/4885
US-20100330013-A1 AMADORIASES IN WASHING AND CLEANING PRODUCTS ALPI, POLR1C, ZAP70 MEN1 416/4885KMT2A 424/4885ALDH1A1 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.