Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.54 |
| ▸ | PREP | P48147 | 1/20 | 0.54 |
| ▸ | FAP | Q12884 | 1/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189052 | 0.86 | NPC1 (0.55) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14259818 | 0.85 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL15808498 | 0.83 | POLB (0.66) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL19423712 | 0.83 | POLB (0.66) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL1027107 | 0.83 | POLB (0.66) | DPP4DPP8PREPFAPDPP9 | |
| Hydrochloric Acid SCHEMBL19410049 | 0.81 | POLB (0.63) | DPP4DPP8PREPFAPDPP9 | |
| Hydrochloric Acid SCHEMBL19410021 | 0.81 | POLB (0.63) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL11892715 | 0.81 | NPC1 (0.54) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL19410019 | 0.81 | POLB (0.63) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL3966250 | 0.81 | L3MBTL1 (0.47) | DPP4DPP8FAPDPP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298834-A1 | 4-(AMINOMETHYL)CYCLOHEXANAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | ZALICUS PHARMACEUTICALS LTD. (CA) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298834-A1 | 4-(AMINOMETHYL)CYCLOHEXANAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | CACNA1G, CACNA1I, CACNA1H | DPP4 2280/4885DPP8 3109/4885PREP 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.