Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18181904 | 0.81 | TSHR (0.63) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL7597607 | 0.81 | MEN1 (0.67) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL11392447 | 0.81 | MEN1 (0.67) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL10415957 | 0.80 | ADRA1B (0.57) | MEN1KMT2AALDH1A1HTR1AADRA1A | |
| SCHEMBL13292998 | 0.79 | MEN1 (0.57) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL13140375 | 0.79 | MEN1 (0.64) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL29342004 | 0.79 | MEN1 (0.64) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL4725263 | 0.78 | DRD2 (0.60) | MEN1KMT2AALDH1A1TSHRHTT | |
| Ammonia Solution, Strong SCHEMBL3580502 | 0.78 | MEN1 (0.55) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL18177816 | 0.77 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891344-A1 | ALPHA 1-ADRENERGIC RECEPTOR ANTAGONISTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997037983-A1 | α1-ADRENERGIC RECEPTOR ANTAGONISTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1997-10-16 | — | — | WO | disclosed |