Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368881 | 0.76 | S100A4 (0.49) | — | |
| SCHEMBL8370523 | 0.75 | S100A4 (0.51) | — | |
| SCHEMBL8368796 | 0.74 | S100A4 (0.58) | — | |
| SCHEMBL8367269 | 0.71 | MALT1 (0.60) | IRAK4 | |
| SCHEMBL8368658 | 0.71 | S100A4 (0.44) | PIM1 | |
| SCHEMBL8368655 | 0.70 | MALT1 (0.41) | PIM1 | |
| SCHEMBL13118498 | 0.63 | ACHE (0.61) | ACHEPIM1 | |
| SCHEMBL1917262 | 0.61 | S100A4 (0.45) | — | |
| SCHEMBL6501841 | 0.61 | MAPT (0.53) | ACHE | |
| SCHEMBL1090507 | 0.61 | CXCR4 (0.55) | ACHEPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052365-A1 | ANTICANCER AGENTS | ELI LILLY AND COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |