SCHEMBL8370619

SCHEMBL8370619

CCCC(=O)C1CNCCN1C(=O)C([C]=O)CC

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.30
F9 P00740 1/20 0.30
F10 P00742 1/20 0.30
F12 P00748 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
F7 P08709 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8369334 0.75 F2 (0.31) F2F9F10F12PRSS1
SCHEMBL4630218 0.74 GNAI3 (0.31)
SCHEMBL6423251 0.71 PARP1 (0.43)
SCHEMBL6285457 0.69 GNAI3 (0.45)
SCHEMBL2850134 0.68 GNAI3 (0.47)
SCHEMBL23658148 0.66 CHRNB2 (0.37)
SCHEMBL23658147 0.66 DPP4 (0.34) F2F9F10F12PRSS1
SCHEMBL27520177 0.65 CHRNB2 (0.33)
SCHEMBL10587925 0.65 CHRNB2 (0.40)
Hydrochloric Acid SCHEMBL17560462 0.64 DPP4 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576095-B1 Immunoassays with labeled thyronine hapten analogues JOHNSON & JOHNSON CLIN DIAG (US) 1999-01-27 EP claimed
EP-0576095-A1 Immunoassays with labeled thyronine hapten analogues Johnson & Johnson Clinical Diagnostics, Inc. (US) 1993-12-29 EP claimed