Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33659 | 0.84 | MAPT (0.46) | ALDH1A1MAPTSIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL15928730 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTSIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL20664230 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTSIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL10412215 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTSIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL4862775 | 0.80 | SIGMAR1 (0.43) | ALDH1A1MAPTSIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL10037099 | 0.78 | RAPGEF4 (0.52) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8372450 | 0.78 | SIGMAR1 (0.42) | ALDH1A1MAPTSIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL5679369 | 0.78 | GSK3B (0.40) | ALDH1A1MAPTCASP1GSK3BMEN1 | |
| SCHEMBL13718688 | 0.78 | GSK3B (0.40) | ALDH1A1MAPTCASP1GSK3BGAA | |
| SCHEMBL29319729 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365127-B1 | Substituted triazines | UNIROYAL CHEM CO INC (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5120844-A | Antiozonants for rubber | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1992-06-09 | — | — | US | disclosed |
| US-4972010-A | OXIDATION RESISTANCE FOR TIRES, RUBBERS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0365127-A1 | Substituted triazines | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1990-04-25 | — | — | EP | disclosed |