Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138308 | 0.77 | RAB9A (0.35) | SMN1; SMN2RAB9ALMNATSHRMAPK1 | |
| SCHEMBL8306233 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ACYP1A2CYP2C19HPGD | |
| SCHEMBL4245180 | 0.73 | RAB9A (0.38) | SMN1; SMN2RAB9AALDH1A1POLBLMNA | |
| SCHEMBL9076935 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AALDH1A1POLBLMNA | |
| SCHEMBL9076246 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9AALDH1A1POLBLMNA | |
| SCHEMBL27524777 | 0.72 | LMNA (0.44) | SMN1; SMN2RAB9ACYP1A2CYP2C19HPGD | |
| SCHEMBL10668544 | 0.71 | RAB9A (0.50) | SMN1; SMN2RAB9ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3436915 | 0.71 | RAB9A (0.36) | SMN1; SMN2RAB9AALDH1A1POLBLMNA | |
| SCHEMBL7949489 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7949349 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11012275-A | — | — | None | — | — | JP | disclosed |
| JP-H1112275-A | TETRAZONE-SUBSTITUTED BENZENE DERIVATIVES AND HERBICIDES | NIPPON SODA CO LTD | 1999-01-19 | — | — | JP | disclosed |