Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310173 | 0.88 | RAB9A (0.36) | SMN1; SMN2RAB9AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5204516 | 0.86 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1HTTNTRK1KMT2A | |
| SCHEMBL8377155 | 0.82 | NTRK1 (0.35) | SMN1; SMN2RAB9AALDH1A1HTTNTRK1 | |
| SCHEMBL8370898 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8712680 | 0.76 | MEN1 (0.34) | RAB9AALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL5204512 | 0.75 | KDM4E (0.43) | RAB9AALDH1A1NTRK1KMT2AMEN1 | |
| SCHEMBL5209607 | 0.75 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1NTRK1KMT2AMEN1 | |
| SCHEMBL27464247 | 0.75 | KDM4E (0.31) | ALDH1A1TSHRKDM4EUSP2CSF1R | |
| SCHEMBL8138308 | 0.74 | RAB9A (0.35) | SMN1; SMN2RAB9AKMT2AMEN1TSHR | |
| SCHEMBL2215157 | 0.74 | CSF1R (0.33) | ALDH1A1KMT2ATSHRKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891972-A1 | 3-(ISOXAZOL-5-YL)-SUBSTITUTED BENZOIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO., LTD. (JP) | 1999-01-20 | — | — | EP | disclosed |