Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFSF11 | O14788 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292047 | 0.84 | KDM4E (0.53) | TNFSF11BACE1CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL862161 | 0.81 | ALDH1A1 (0.56) | CYP3A4USP2MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL25404611 | 0.81 | POLB (0.58) | TNFSF11BACE1CYP3A4POLBTSHR | |
| SCHEMBL3326825 | 0.80 | TUBB4A (0.63) | TNFSF11BACE1CYP3A4USP2MAPK1 | |
| SCHEMBL16521510 | 0.79 | ALOX5 (0.48) | TNFSF11BACE1CYP3A4USP2MAPK1 | |
| SCHEMBL13021618 | 0.77 | ELANE (0.50) | TNFSF11BACE1MAPK1SMN1; SMN2POLB | |
| SCHEMBL3328971 | 0.77 | TSHR (0.64) | TNFSF11BACE1TSHRKMT2ATUBB4A | |
| SCHEMBL3327344 | 0.77 | CA12 (0.63) | TNFSF11BACE1TSHRKMT2ATUBB4A | |
| SCHEMBL28919121 | 0.75 | KMT2A (0.55) | TNFSF11BACE1CYP3A4USP2MAPK1 | |
| SCHEMBL919577 | 0.74 | ALDH1A1 (0.55) | TNFSF11BACE1CYP3A4USP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892067-A1 | FLUORESCENT ENZYME SUBSTRATES AND METHOD FOR ASSAYING ENZYMATIC ACTIVITY | Laboratory of Molecular Biophotonics (JP) | 1999-01-20 | — | — | EP | disclosed |