Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474626 | 0.71 | CA12 (0.43) | TTRKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10415958 | 0.71 | CA12 (0.43) | TTRKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8375398 | 0.70 | HSD17B10 (0.62) | POLBPOLA1ANTXR2TPMTMAPT | |
| SCHEMBL18263212 | 0.68 | LMNA (0.50) | MAPTKMT2ACRHBPHTTCRHR2 | |
| SCHEMBL8044565 | 0.67 | HSD17B10 (0.57) | POLBPOLA1ANTXR2TPMTMAPT | |
| SCHEMBL9174491 | 0.66 | HSD17B10 (0.43) | TTRTPMTMAPTKMT2ACRHBP | |
| SCHEMBL421547 | 0.66 | MAPT (0.51) | TPMTMAPTKMT2AHTTALDH1A1 | |
| SCHEMBL6930173 | 0.66 | HSD17B10 (0.51) | POLBTPMTMAPTALDH1A1KDM4E | |
| SCHEMBL6939130 | 0.66 | MAPT (0.47) | POLBMAPTKMT2ACRHBPHTT | |
| SCHEMBL9173276 | 0.66 | HTT (0.47) | POLBMAPTKMT2ACRHBPHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669940-B1 | SPECIFICALLY CROSSLINKED HEMOGLOBIN WITH FREE FUNCTIONALITY | UNIV TORONTO (CA) | 1999-02-10 | — | — | EP | claimed |