Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375683 | 0.85 | TTR (0.53) | GPR35ALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL7766735 | 0.82 | GPR35 (0.49) | GPR35ALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL1600086 | 0.81 | GPR35 (0.65) | GPR35ALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL247818 | 0.78 | ESR1 (0.48) | ALDH1A1CYP3A4TTRKDM4EMEN1 | |
| SCHEMBL24191114 | 0.75 | GPR35 (0.56) | GPR35ALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL30429503 | 0.75 | GPR35 (0.56) | GPR35ALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL17744391 | 0.75 | GPR35 (0.65) | GPR35ALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL29837196 | 0.75 | ALDH1A1 (0.53) | GPR35ALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL31447707 | 0.75 | ALDH1A1 (0.53) | GPR35ALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL4649869 | 0.75 | ALDH1A1 (0.53) | GPR35ALDH1A1HPGDALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977413-A | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0895985-A2 | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | Nippon Kayaku Kabushiki Kaisha (JP) | 1999-02-10 | — | — | EP | disclosed |